Its duration of action is a factor in how long it will affect you. The common side effects of Wellbutrin include headache, weight loss, dry mouth, insomnia, nausea, and constipation. You might also experience an irregular or fast heart rate, moodiness, or restlessness.
Less common but more severe side effects could include seizures, cardiovascular heart and blood vessel problems, or worsening depression. Those taking Wellbutrin for smoking cessation might notice a change in their mood, for better or worse. Talk to your doctor about any worsening of your depressive symptoms or the onset of panic attacks or suicidal thoughts. The severity of side effects also may depend on certain existing medical conditions you may have, including high blood pressure, irregularities in your heartbeat, a brain tumor, liver disease, substance use disorder, or eating disorders.
Be sure to talk with your doctor before taking Wellbutrin if you have a history of any of these conditions. You can also discuss any concerns with one of the professionals at Minded. The FDA has put Wellbutrin in category B for pregnancy, meaning that animal studies have not shown risk to the fetus.
There are no adequate studies on its effect on humans, so we cannot rule out the risk of taking Wellbutrin if you are pregnant. Because depression can negatively impact your pregnancy or the care of your infant, it is essential for you and your doctor to consider the risks and benefits of using it.
Wellbutrin is carried by breast milk to a nursing child. If you are prone to seizures, drinking alcohol with Wellbutrin can increase the risk of having them. Consult with your doctor or a Minded clinician about any other medications you are taking to consider if Wellbutrin will cause any adverse problematic drug interactions. Most people report mild to no withdrawal symptoms from Wellbutrin. Lexapro, the brand name of the generic drug escitalopram, was approved in It is an SSRI.
It is mainly used for depression and major depression, as well as anxiety and generalized anxiety disorder GAD. People who take Lexapro report improvements in energy, sleep quality, mood, and appetite, often within weeks. With more serious conditions, improvements may take weeks.
The typical dosage for Lexapro is mg per day, depending on your age, weight, any medical problems you may have, and other medications and supplements you may be taking. Off-label uses of Lexapro include treatment for obsessive-compulsive disorders OCD and panic disorders. Some individuals experience sexual side effects, including sexual arousal disorder, sexual desire disorder, and orgasm dysfunction.
Many people experience reduced sex drive or decreased libido as a side effect. Weight gain is not common on Lexapro. But if decreased appetite was one of your reasons for taking Lexapro, you may experience weight gain from an improvement in your appetite.
Lexapro can worsen depression symptoms, so immediately speak with your doctor or therapist if you experience suicidal thoughts. Severe side effects can occur with Lexapro, like high blood pressure, also known as hypertension. Lexapro also may cause serotonin syndrome , characterized by symptoms that include agitation, fever, hallucinations, diarrhea, heartbeat irregularities, and restlessness.
If that happens, contact your doctor immediately. Lexapro is in category C for pregnancy, which means there have been animal studies that show a potentially harmful effect on the fetus. Not enough studies have been done to confirm the risk on human fetuses.
Lexapro is available as an oral tablet in strengths of 5 mg, 10 mg, and 20 mg. Sign up for Lexapro price alerts and find out when the price changes! Get price alerts. Wellbutrin and Lexapro are both indicated in the treatment of major depression.
MDD is characterized by prolonged 2 weeks or more feelings of low mood and decreased energy levels. It is possible that patients may not find joy in things they enjoyed previously. Lexapro is also indicated in the treatment of generalized anxiety disorder GAD. GAD is characterized by prolonged and obsessive worrying about a variety of topics. Bupropion, the active ingredient in Wellbutrin, carries a unique indication for smoking cessation.
Although the mechanism is not entirely understood, patients taking bupropion are more likely to be able to achieve smoking cessation. A systematic review of numerous studies with an overall large sample size supports this statement, though patients may experience more adverse events than with other smoking cessation interventions. Wellbutrin and Lexapro are both used off-label in a variety of psychological disorders that are closely related to depression.
The following is not intended to be a complete listing of potential uses for Wellbutrin and Lexapro. Only your healthcare professional can diagnose your disorder and decide which treatment option is best for you. Researchers have sought to compare Wellbutrin and Lexapro both as singular therapy for MDD, as well as dual therapy. One trial evaluated the efficacy of Wellbutrin as single therapy as compared to Lexapro single therapy. This study also sought to compare the prevalence of negative sexual side effects.
The results found that Wellbutrin and Lexapro produced similar improvements in depressive symptoms, however, Wellbutrin was significantly less likely to cause sexual dysfunction. Wellbutrin and Lexapro affect different neurotransmitters and are oftentimes used together.
The results of one clinical trial found that the use of both drugs together leads to significantly higher response and symptom remission rates as compared to typical monotherapy with SSRIs.
While further studies may be warranted, this study suggests some value in dual therapy with both medications. Sign up for Wellbutrin price alerts and find out when the price changes!
Wellbutrin is a prescription medication that is typically covered by both commercial and Medicare drug plans. Lexapro is also a prescription medication that is typically covered by both commercial and Medicare drug plans.
Try the SingleCare prescription discount card. Wellbutrin and Lexapro affect the levels of different neurotransmitters. While their potential to cause certain side effects may be similar, there are some key differences. Lexapro, like other SSRIs, has the potential to cause decreased libido or sex drive. Wellbutrin had no reported incidence of decreased libido.
Wellbutrin causes headache in as much as a quarter of the patients who take it, while headaches were not reported with Lexapro. Wellbutrin and Lexapro both may cause nausea, vomiting, sweating, and diarrhea. The following list is not intended to be a complete list of adverse events. Please consult a pharmacist, doctor, or another medical professional for a complete list of possible side effects. If co-administration of Wellbutrin and a CYP2D6 substrate is needed, it may be necessary to decrease the dose of the 2D6 substrate.
Some examples of CYP2D6 substrates include fluoxetine, sertraline, haloperidol, risperidone, and metoprolol. The use of Lexapro with tricyclic antidepressants, such as amitriptyline, may increase the risk of QT prolongation and serotonin syndrome.
In general, this combination should be avoided. The following list is not intended to be a complete list of drug interactions. It is best to consult your provider or pharmacist for a complete list. Patients with MDD may experience a worsening of depression or suicidal thoughts whether or not they are taking antidepressant medications. These conditions may worsen until remission is achieved. Wellbutrin and Lexapro therapy may increase suicidal ideation and thoughts among teens and young adults, especially in the early stages of treatment before any type of remission is achieved.
These patients must be monitored closely if this treatment is deemed medically necessary. In a study of antidepressants and weight gain, researchers found that bupropion was the only medication that produced weight loss. Another study found that bupropion enhanced weight loss in obese adults over a period of 48 weeks.
In short, research shows that Lexapro usually causes a small amount of weight gain, whereas Wellbutrin is more commonly associated with weight loss.
Finally, when it comes to effectiveness, research largely shows that Wellbutrin and Lexapro are both reliable treatments for depression. In one study , researchers compared the effectiveness of Wellbutrin and Lexapro in people with moderate to severe depression. The study participants received either generic bupropion, generic escitalopram or a placebo for eight weeks, with their depression symptoms tracked and monitored using the Hamilton Rating Scale for Depression HAM-D and Hospital Anxiety and Depression HAD scale.
The researchers concluded that the medications were similarly effective at treating depression, but that bupropion was less likely to cause sexual side effects. Other research has found that Wellbutrin and Lexapro are especially effective when used as a form of combination therapy. In short, both medications work well. In addition to Wellbutrin and Lexapro, numerous other medications are used to treat depression and anxiety disorders.
These include:. Selective serotonin reuptake inhibitors SSRIs. Serotonin-norepinephrine reuptake inhibitors SNRIs. Older classes of antidepressants. In certain cases, older antidepressants, such as tricyclic antidepressants TCAs and monoamine oxidase inhibitors MAOIs are also prescribed to treat depression. This full list of antidepressants provides more information on these medications, their effects, side effects and more.
Wellbutrin and Lexapro are similar medications. Both are antidepressants supported by a large amount of scientific research, and both have a long track record of producing improvements—often significant. However, when examining Wellbutrin vs. You can find a range of mental health care services online, including options such as online psychiatry , individual online counseling , and online support groups.
We rely on peer-reviewed studies, academic research institutions, and medical associations. We strive to use primary sources and refrain from using tertiary references. This article is for informational purposes only and does not constitute medical advice. The information contained herein is not a substitute for and should never be relied upon for professional medical advice.
Always talk to your doctor about the risks and benefits of any treatment. Insider tips, early access and more. What We Treat. Sexual health. Mental Health. Top treatments. Read on to learn more about Wellbutrin vs. Lexapro, and how each medication works in detail. What is Wellbutrin Bupropion? What is Lexapro Escitalopram? Wellbutrin vs.
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