You can also search for this author in PubMed Google Scholar. Correspondence to Vinodkumar Singh MD. Reprints and Permissions. Singh, V. Ondansetron-induced migraine-type headache. Download citation. Received : 19 May Accepted : 10 June Published : 27 July Issue Date : September Anyone you share the following link with will be able to read this content:. Sorry, a shareable link is not currently available for this article.
Provided by the Springer Nature SharedIt content-sharing initiative. Skip to main content. You may opt-out of e-mail communications at any time by clicking on the Unsubscribe link in the e-mail. Our Housecall e-newsletter will keep you up-to-date on the latest health information. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.
Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. This site complies with the HONcode standard for trustworthy health information: verify here. This means it takes the body three to four hours to eliminate half a dose of Zofran from the body, so the entire dose should be eliminated in 15 to 20 hours.
Some more serious side effects may take longer to resolve. Some, like serotonin syndrome , severe allergic reactions , or heart rhythm abnormalities , may require emergency medical treatment to get better. Severe heart rhythm problems, however, may produce lifelong complications. Physical and medical conditions may affect the safety or effectiveness of Zofran , so some people may not be able to take Zofran and others may require dosing changes or closer monitoring for adverse reactions.
The U. Food and Drug Administration FDA does not classify ondansetron as a controlled substance, meaning it has no potential for abuse or physical dependence. Ondansetron is given either as a single dose or for no longer than a few days during cancer treatment , radiation treatment , or surgery. Withdrawal symptoms are not experienced when ondansetron treatment is discontinued.
An overdose of Zofran can be a serious medical emergency or even fatal , so get emergency medical attention if too much Zofran has been taken. A Zofran overdose will cause symptoms such as temporary vision loss, severe constipation , light-headedness, and fainting.
In addition, serotonin syndrome has been reported in children who have overdosed on Zofran. When a drug is never given to people with certain medical conditions , those medical conditions are called contraindications. Zofran is contraindicated in people who have a known hypersensitivity to ondansetron because of the risk of severe allergic reactions. Zofran is also contraindicated in people who have congenital long QT syndrome because of the risk of serious heart rhythm abnormalities.
Healthcare professionals will avoid Zofran or use it cautiously in people with certain medical conditions such as:. There is not enough research about the use of ondansetron during pregnancy or breastfeeding to be certain if it is safe for an unborn baby or infant. There is currently no evidence that ondansetron has caused birth defects , miscarriages, or harm to a breastfeeding infant. Pregnant or nursing women should consult a healthcare professional before taking Zofran. In those patients complaining of severe headache, the Authors suggest an antiemetic association, with a loading dose of ondansetron i.
Abstract Chemotherapy-induced emesis is one of the major problems in the treatment of oncologic patients.
0コメント